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Visualization of ligand-induced dopamine D(2S) and D(2L) receptor internalization by TIRF microscopy
G protein-coupled receptors (GPCRs), including the dopamine receptors, represent a group of important pharmacological targets. Upon agonist binding, GPCRs frequently undergo internalization, a process that is known to attenuate functional responses upon prolonged exposure to agonists. In this study,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589927/ https://www.ncbi.nlm.nih.gov/pubmed/28883522 http://dx.doi.org/10.1038/s41598-017-11436-1 |