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Ex vivo T-cell depletion in allogeneic hematopoietic stem cell transplant: past, present and future
The most common cause of post-transplant mortality in patients with hematological malignancy is relapse, followed by GvHD, infections, organ toxicity and second malignancy. Immune-mediated complications such as GvHD continue to be challenging, yet amenable to control through manipulation of the T-ce...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589981/ https://www.ncbi.nlm.nih.gov/pubmed/28319073 http://dx.doi.org/10.1038/bmt.2017.22 |