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Ex vivo T-cell depletion in allogeneic hematopoietic stem cell transplant: past, present and future

The most common cause of post-transplant mortality in patients with hematological malignancy is relapse, followed by GvHD, infections, organ toxicity and second malignancy. Immune-mediated complications such as GvHD continue to be challenging, yet amenable to control through manipulation of the T-ce...

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Detalles Bibliográficos
Autores principales: Saad, A, Lamb, L S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589981/
https://www.ncbi.nlm.nih.gov/pubmed/28319073
http://dx.doi.org/10.1038/bmt.2017.22