Cargando…

Intracrine VEGF signalling mediates colorectal cancer cell migration and invasion

BACKGROUND: Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) are key regulators of angiogenesis, affecting endothelial cell survival and function. However, the effect of VEGF-VEGFR signalling on tumour cell function is not well understood. Our previous studies in colorectal cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhattacharya, Rajat, Fan, Fan, Wang, Rui, Ye, Xiangcang, Xia, Ling, Boulbes, Delphine, Ellis, Lee M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589988/ https://www.ncbi.nlm.nih.gov/pubmed/28742793 http://dx.doi.org/10.1038/bjc.2017.238

Ejemplares similares

A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling
por: Wang, Rui, et al.
Publicado: (2016)

Endothelial cells activate the cancer stem cell‐associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion
por: Wang, Rui, et al.
Publicado: (2017)

Intracrine androgen biosynthesis in renal cell carcinoma
por: Lee, Geun Taek, et al.
Publicado: (2017)

Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway
por: Fan, Fan, et al.
Publicado: (2018)

The requirement for freshly isolated human colorectal cancer (CRC) cells in isolating CRC stem cells
por: Fan, F, et al.
Publicado: (2015)

Cytospin-A Regulates Colorectal Cancer Cell Division and Migration by Modulating Stability of Microtubules and Actin Filaments
por: Fan, Fan, et al.
Publicado: (2022)

Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases
por: Lesslie, D P, et al.
Publicado: (2006)

Exploring the Intracrine Functions of VEGF-A
por: Wiszniak, Sophie, et al.
Publicado: (2021)

Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells
por: Bose, D, et al.
Publicado: (2011)

Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion
por: Meng, X N, et al.
Publicado: (2009)

Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma
por: Pritchard-Jones, R O, et al.
Publicado: (2007)

Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer
por: Kut, C, et al.
Publicado: (2007)

Intracrine Vascular Endothelial Growth Factor Signaling in Survival and Chemoresistance of Human Colorectal Cancer Cells
por: Samuel, Shaija, et al.
Publicado: (2010)

VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo
por: Rennel, E S, et al.
Publicado: (2009)

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
por: Braig, S, et al.
Publicado: (2011)

VEGF directly suppresses activation of T cells from ascites secondary to ovarian cancer via VEGF receptor type 2
por: Gavalas, N G, et al.
Publicado: (2012)

MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells
por: Chandrasekaran, Karthik Subramanian, et al.
Publicado: (2016)

The influence of invasive growth pattern and microvessel density on prognosis in colorectal cancer and colorectal liver metastases
por: Rajaganeshan, R, et al.
Publicado: (2007)

TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells
por: Mu, Y, et al.
Publicado: (2015)

BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM
por: Wei, Fang, et al.
Publicado: (2018)

Arachidonic acid induction of Rho-mediated transendothelial migration in prostate cancer
por: Brown, M, et al.
Publicado: (2014)

Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer
por: Park, J H, et al.
Publicado: (2017)

Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma
por: Yoshikawa, D, et al.
Publicado: (2008)

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors
por: Bijnsdorp, I V, et al.
Publicado: (2011)

Farnesoid X receptor, overexpressed in pancreatic cancer with lymph node metastasis promotes cell migration and invasion
por: Lee, J Y, et al.
Publicado: (2011)

Serum endostatin levels are elevated in colorectal cancer and correlate with invasion and systemic inflammatory markers
por: Kantola, T, et al.
Publicado: (2014)

Potent anti-tumour activity of a novel conditionally replicating adenovirus for melanoma via inhibition of migration and invasion
por: Jiang, G, et al.
Publicado: (2014)

Elastin peptides regulate HT-1080 fibrosarcoma cell migration and invasion through an Hsp90-dependent mechanism
por: Donet, M, et al.
Publicado: (2014)

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
por: Chen, J, et al.
Publicado: (2010)

Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion
por: Byrne, Anne-Marie, et al.
Publicado: (2015)

EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer
por: Youssef, M M S, et al.
Publicado: (2006)

Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?
por: Karayan-Tapon, L, et al.
Publicado: (2008)

Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer
por: Sasahira, T, et al.
Publicado: (2012)

Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway
por: Joshi, H, et al.
Publicado: (2012)

Platelet releasate promotes breast cancer growth and angiogenesis via VEGF–integrin cooperative signalling
por: Jiang, Lei, et al.
Publicado: (2017)

HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation
por: Jung, C, et al.
Publicado: (2005)

Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation
por: Grunewald, T G P, et al.
Publicado: (2007)

Leptin-mediated regulation of ICAM-1 is Rho/ROCK dependent and enhances gastric cancer cell migration
por: Dong, Z, et al.
Publicado: (2014)

FMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer
por: Yang, S S, et al.
Publicado: (2017)

Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion
por: Berthier-Vergnes, O, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_k0oritpk8dhce49pq8vm199t30