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Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline

Approximately 1.4 million women living with HIV become pregnant every year. Most women use antiretroviral therapy, to reduce the risk of vertical transmission or for personal health reasons. Using the GRADE framework according to the BMJ Rapid Recommendation process, we make recommendations for opti...

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Autores principales: Siemieniuk, Reed A C, Lytvyn, Lyubov, Mah Ming, Jinell, Mullen, Rhonda Marama, Anam, Florence, Otieno, Teresia, Guyatt, Gordon H, Taylor, Graham P, Beltrán-Arroyave, Claudia, Okwen, Patrick Mbah, Nduati, Ruth, Kinuthia, John, Luma, Henry Namme, Kirpalani, Haresh, Merglen, Arnaud, Lesi, Olufunmilayo A, Vandvik, Per Olav, Agoritsas, Thomas, Bewley, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590100/
https://www.ncbi.nlm.nih.gov/pubmed/28893728
http://dx.doi.org/10.1136/bmj.j3961
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author Siemieniuk, Reed A C
Lytvyn, Lyubov
Mah Ming, Jinell
Mullen, Rhonda Marama
Anam, Florence
Otieno, Teresia
Guyatt, Gordon H
Taylor, Graham P
Beltrán-Arroyave, Claudia
Okwen, Patrick Mbah
Nduati, Ruth
Kinuthia, John
Luma, Henry Namme
Kirpalani, Haresh
Merglen, Arnaud
Lesi, Olufunmilayo A
Vandvik, Per Olav
Agoritsas, Thomas
Bewley, Susan
author_facet Siemieniuk, Reed A C
Lytvyn, Lyubov
Mah Ming, Jinell
Mullen, Rhonda Marama
Anam, Florence
Otieno, Teresia
Guyatt, Gordon H
Taylor, Graham P
Beltrán-Arroyave, Claudia
Okwen, Patrick Mbah
Nduati, Ruth
Kinuthia, John
Luma, Henry Namme
Kirpalani, Haresh
Merglen, Arnaud
Lesi, Olufunmilayo A
Vandvik, Per Olav
Agoritsas, Thomas
Bewley, Susan
author_sort Siemieniuk, Reed A C
collection PubMed
description Approximately 1.4 million women living with HIV become pregnant every year. Most women use antiretroviral therapy, to reduce the risk of vertical transmission or for personal health reasons. Using the GRADE framework according to the BMJ Rapid Recommendation process, we make recommendations for optimal choice of combination antiretroviral regimen considering patient values and preferences, the balance of desirable and undesirable outcomes, their uncertainty, and practical issues. We suggest a zidovudine and lamivudine-based regimen over one that includes tenofovir or emtricitabine (weak recommendation). We recommend alternatives over the combination of tenofovir, emtricitabine, and lopinavir/ritonavir (strong recommendation).
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spelling pubmed-55901002017-09-14 Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline Siemieniuk, Reed A C Lytvyn, Lyubov Mah Ming, Jinell Mullen, Rhonda Marama Anam, Florence Otieno, Teresia Guyatt, Gordon H Taylor, Graham P Beltrán-Arroyave, Claudia Okwen, Patrick Mbah Nduati, Ruth Kinuthia, John Luma, Henry Namme Kirpalani, Haresh Merglen, Arnaud Lesi, Olufunmilayo A Vandvik, Per Olav Agoritsas, Thomas Bewley, Susan BMJ Practice Approximately 1.4 million women living with HIV become pregnant every year. Most women use antiretroviral therapy, to reduce the risk of vertical transmission or for personal health reasons. Using the GRADE framework according to the BMJ Rapid Recommendation process, we make recommendations for optimal choice of combination antiretroviral regimen considering patient values and preferences, the balance of desirable and undesirable outcomes, their uncertainty, and practical issues. We suggest a zidovudine and lamivudine-based regimen over one that includes tenofovir or emtricitabine (weak recommendation). We recommend alternatives over the combination of tenofovir, emtricitabine, and lopinavir/ritonavir (strong recommendation). BMJ Publishing Group Ltd. 2017-09-11 /pmc/articles/PMC5590100/ /pubmed/28893728 http://dx.doi.org/10.1136/bmj.j3961 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Practice
Siemieniuk, Reed A C
Lytvyn, Lyubov
Mah Ming, Jinell
Mullen, Rhonda Marama
Anam, Florence
Otieno, Teresia
Guyatt, Gordon H
Taylor, Graham P
Beltrán-Arroyave, Claudia
Okwen, Patrick Mbah
Nduati, Ruth
Kinuthia, John
Luma, Henry Namme
Kirpalani, Haresh
Merglen, Arnaud
Lesi, Olufunmilayo A
Vandvik, Per Olav
Agoritsas, Thomas
Bewley, Susan
Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline
title Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline
title_full Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline
title_fullStr Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline
title_full_unstemmed Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline
title_short Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline
title_sort antiretroviral therapy in pregnant women living with hiv: a clinical practice guideline
topic Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590100/
https://www.ncbi.nlm.nih.gov/pubmed/28893728
http://dx.doi.org/10.1136/bmj.j3961
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