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Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells

BACKGROUND: The distal convoluted tubule (DCT) is an important nephron site for parathyroid hormone (PTH) and calcitonin regulation of urinary divalent cation excretion. These hormones exert their effects on the DCT in substantial part through activation of adenylyl cyclase (AC); however, it is unkn...

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Detalles Bibliográficos
Autores principales: Kittikulsuth, Wararat, Friedman, Peter A., van Hoek, Alfred, Gao, Yang, Kohan, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590165/
https://www.ncbi.nlm.nih.gov/pubmed/28882112
http://dx.doi.org/10.1186/s12882-017-0712-5