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Is cytotoxicity a determinant of the different in vitro and in vivo effects of bioactives?

BACKGROUND: Foodstuffs of both plant and animal origin contain a wide range of bioactive compounds. Although human intervention studies are mandatory to assess the health effects of bioactives, the in vitro approach is often used to select the most promising molecules to be studied in vivo. To avoid...

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Detalles Bibliográficos
Autores principales: Di Nunzio, Mattia, Valli, Veronica, Tomás-Cobos, Lidia, Tomás-Chisbert, Teresa, Murgui-Bosch, Lucía, Danesi, Francesca, Bordoni, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590171/
https://www.ncbi.nlm.nih.gov/pubmed/28882181
http://dx.doi.org/10.1186/s12906-017-1962-2

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