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Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model

BACKGROUND: Alexander disease (AxD) is an astrogliopathy that predominantly affects the white matter of the central nervous system (CNS), and is caused by a mutation in the gene encoding the glial fibrillary acidic protein (GFAP), an intermediate filament primarily expressed in astrocytes and ependy...

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Detalles Bibliográficos
Autores principales:	Lee, So-Hyun, Nam, Tai-Seung, Kim, Kun-Hee, Kim, Jin Hee, Yoon, Woong, Heo, Suk-Hee, Kim, Min Jung, Shin, Boo Ahn, Perng, Ming-Der, Choy, Hyon E., Jo, Jihoon, Kim, Myeong-Kyu, Choi, Seok-Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590178/ https://www.ncbi.nlm.nih.gov/pubmed/28882119 http://dx.doi.org/10.1186/s12883-017-0938-7

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