High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods

BACKGROUND: Next generation sequencing (NGS) is being increasingly applied for assisting cancer molecular diagnosis. However, it is still needed to validate NGS accuracy on detection of DNA alternations based on a large number of clinical samples, especially for DNA rearrangements and copy number va...

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Detalles Bibliográficos
Autores principales: Su, Dan, Zhang, Dadong, Chen, Kaiyan, Lu, Jing, Wu, Junzhou, Cao, Xinkai, Ying, Lisha, Jin, Qihuang, Ye, Yizhou, Xie, Zhenghua, Xiong, Lei, Mao, Weimin, Li, Fugen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590190/
https://www.ncbi.nlm.nih.gov/pubmed/28882180
http://dx.doi.org/10.1186/s13046-017-0591-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590190/
https://www.ncbi.nlm.nih.gov/pubmed/28882180
http://dx.doi.org/10.1186/s13046-017-0591-4

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