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High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods
BACKGROUND: Next generation sequencing (NGS) is being increasingly applied for assisting cancer molecular diagnosis. However, it is still needed to validate NGS accuracy on detection of DNA alternations based on a large number of clinical samples, especially for DNA rearrangements and copy number va...
Autores principales: | Su, Dan, Zhang, Dadong, Chen, Kaiyan, Lu, Jing, Wu, Junzhou, Cao, Xinkai, Ying, Lisha, Jin, Qihuang, Ye, Yizhou, Xie, Zhenghua, Xiong, Lei, Mao, Weimin, Li, Fugen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590190/ https://www.ncbi.nlm.nih.gov/pubmed/28882180 http://dx.doi.org/10.1186/s13046-017-0591-4 |
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