Review of commercially available demineralized bone matrix products for spinal fusions: A selection paradigm

BACKGROUND: Spinal fusions are commonly performed in the US each year for various spinal pathologies. There are multiple commercially available graft material options for these procedures, including an abundance of demineralized bone matrix (DBM) products. METHODS: This study reviews, clearly organizes, and puts forth meaningful information on select biological and physical properties of several commercially available DBM products. In addition, we provide an alternative classification method of DBM products by carrier. RESULTS: This review takes a closer look at the commercial and distributor practices of these products and companies in order to increase transparency between the consumer and source companies. CONCLUSIONS: We propose a novel patient-centered approach to DBM product selection. This requires prioritizing patient safety, product effectiveness, and product transparency. This review offers a practical paradigm to facilitate informed product choice for surgeons and hospital systems alike.