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Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra from Fed-Batch Fermentation Samples

The current work investigates the capability of a tailored multivariate curve resolution–alternating least squares (MCR-ALS) algorithm to analyse glucose, phosphate, ammonium and acetate dynamics simultaneously in an E. coli BL21 fed-batch fermentation. The high-cell-density (HCDC) process is monito...

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Detalles Bibliográficos
Autores principales:	Vier, Dennis, Wambach, Stefan, Schünemann, Volker, Gollmer, Klaus-Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590442/ https://www.ncbi.nlm.nih.gov/pubmed/28952488 http://dx.doi.org/10.3390/bioengineering4010009

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