Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria

Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles. However, they can also cause life-threatening bodily damage. One of the most important p...

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Autores principales: Gil, Dmitry, Rodriguez, Jeannette, Ward, Brendan, Vertegel, Alexey, Ivanov, Vladimir, Reukov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590447/
https://www.ncbi.nlm.nih.gov/pubmed/28952497
http://dx.doi.org/10.3390/bioengineering4010018
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author Gil, Dmitry
Rodriguez, Jeannette
Ward, Brendan
Vertegel, Alexey
Ivanov, Vladimir
Reukov, Vladimir
author_facet Gil, Dmitry
Rodriguez, Jeannette
Ward, Brendan
Vertegel, Alexey
Ivanov, Vladimir
Reukov, Vladimir
author_sort Gil, Dmitry
collection PubMed
description Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles. However, they can also cause life-threatening bodily damage. One of the most important properties of nanocrystalline cerium dioxide is its antioxidant activity, which decreases the abundance of reactive oxygen species during inflammation. In this paper, we report on synergistic effects of inorganic cerium oxide (IV) nanoparticles conjugated with the antioxidative enzymes superoxide dismutase and catalase on scavenging oxygen and nitrogen radicals.
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spelling pubmed-55904472017-09-21 Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria Gil, Dmitry Rodriguez, Jeannette Ward, Brendan Vertegel, Alexey Ivanov, Vladimir Reukov, Vladimir Bioengineering (Basel) Communication Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles. However, they can also cause life-threatening bodily damage. One of the most important properties of nanocrystalline cerium dioxide is its antioxidant activity, which decreases the abundance of reactive oxygen species during inflammation. In this paper, we report on synergistic effects of inorganic cerium oxide (IV) nanoparticles conjugated with the antioxidative enzymes superoxide dismutase and catalase on scavenging oxygen and nitrogen radicals. MDPI 2017-02-25 /pmc/articles/PMC5590447/ /pubmed/28952497 http://dx.doi.org/10.3390/bioengineering4010018 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Gil, Dmitry
Rodriguez, Jeannette
Ward, Brendan
Vertegel, Alexey
Ivanov, Vladimir
Reukov, Vladimir
Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria
title Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria
title_full Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria
title_fullStr Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria
title_full_unstemmed Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria
title_short Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria
title_sort antioxidant activity of sod and catalase conjugated with nanocrystalline ceria
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590447/
https://www.ncbi.nlm.nih.gov/pubmed/28952497
http://dx.doi.org/10.3390/bioengineering4010018
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AT vertegelalexey antioxidantactivityofsodandcatalaseconjugatedwithnanocrystallineceria
AT ivanovvladimir antioxidantactivityofsodandcatalaseconjugatedwithnanocrystallineceria
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