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Assessing and Resolving Model Misspecifications in Metabolic Flux Analysis

Metabolic flux analysis (MFA) is an indispensable tool in metabolic engineering. The simplest variant of MFA relies on an overdetermined stoichiometric model of the cell’s metabolism under the pseudo-steady state assumption to evaluate the intracellular flux distribution. Despite its long history, t...

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Detalles Bibliográficos
Autores principales:	Gunawan, Rudiyanto, Hutter, Sandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590471/ https://www.ncbi.nlm.nih.gov/pubmed/28952528 http://dx.doi.org/10.3390/bioengineering4020048

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