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Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor

Extensive expansion of mesenchymal stem cells (MSCs) for cell-based therapies remains challenging since long-term cultivation and excessive passaging in two-dimensional conditions result in a loss of essential stem cell properties. Indeed, low survival rate of cells, alteration of surface marker pro...

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Detalles Bibliográficos
Autores principales:	Egger, Dominik, Schwedhelm, Ivo, Hansmann, Jan, Kasper, Cornelia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590473/ https://www.ncbi.nlm.nih.gov/pubmed/28952526 http://dx.doi.org/10.3390/bioengineering4020047

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