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In-silico combinatorial design and pharmacophore modeling of potent antimalarial 4-anilinoquinolines utilizing QSAR and computed descriptors
There are very few studies for combinatorial library design and high throughput screening of 4-anilinoquinoline antimalarial compounds having activities against parasitic strain of P. falciparum. Therefore, an attempt has been made in the present paper to design potent lead compounds in this congene...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590512/ https://www.ncbi.nlm.nih.gov/pubmed/29021931 http://dx.doi.org/10.1186/s40064-015-1593-3 |