Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway

BACKGROUND: Translation initiation is the rate limiting step of protein synthesis and is highly regulated. Eukaryotic initiation factor 3C (EIF3C), an oncogene overexpressed in several human cancers, plays an important role in tumorigenesis and cell proliferation. MATERIAL/METHODS: Immunohistochemis...

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Detalles Bibliográficos
Autores principales: Zhao, Weipeng, Li, Xichuan, Wang, Jun, Wang, Chen, Jia, Yongsheng, Yuan, Shunzong, Huang, Yong, Shi, Yehui, Tong, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590544/
https://www.ncbi.nlm.nih.gov/pubmed/28854163
http://dx.doi.org/10.12659/MSM.906389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590544/
https://www.ncbi.nlm.nih.gov/pubmed/28854163
http://dx.doi.org/10.12659/MSM.906389

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