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A heterochromatin-dependent transcription machinery drives piRNA expression

Nuclear small RNA pathways safeguard genome integrity by establishing transcription-repressing heterochromatin at transposable elements. This inevitably also targets the transposon-rich source loci of the small RNAs themselves. How small RNA source loci are efficiently transcribed while transposon p...

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Detalles Bibliográficos
Autores principales: Andersen, Peter Refsing, Tirian, Laszlo, Vunjak, Milica, Brennecke, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590728/
https://www.ncbi.nlm.nih.gov/pubmed/28847004
http://dx.doi.org/10.1038/nature23482