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LncRNA MEG3 Regulates Imatinib Resistance in Chronic Myeloid Leukemia via Suppressing MicroRNA-21

Imatinib resistance has become a major clinical problem for chronic myeloid leukemia. The aim of the present study was to investigate the involvement of MEG3, a lncRNA, in imatinib resistance and demonstrate its underlying mechanisms. RNAs were extracted from CML patients’ peripheral blood cells and...

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Detalles Bibliográficos
Autores principales: Zhou, Xiangyu, Yuan, Ping, Liu, Qi, Liu, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590792/
https://www.ncbi.nlm.nih.gov/pubmed/28190319
http://dx.doi.org/10.4062/biomolther.2016.162