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Analysis of the whole transcriptome from gingivo-buccal squamous cell carcinoma reveals deregulated immune landscape and suggests targets for immunotherapy

BACKGROUND: Gingivo-buccal squamous cell carcinoma (GBSCC) is one of the most common oral cavity cancers in India with less than 50% patients surviving past 5 years. Here, we report a whole transcriptome profile on a batch of GBSCC tumours with diverse tobacco usage habits. The study provides an ent...

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Detalles Bibliográficos
Autores principales: Singh, Richa, De Sarkar, Navonil, Sarkar, Sumanta, Roy, Roshni, Chattopadhyay, Esita, Ray, Anindita, Biswas, Nidhan K., Maitra, Arindam, Roy, Bidyut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590820/
https://www.ncbi.nlm.nih.gov/pubmed/28886030
http://dx.doi.org/10.1371/journal.pone.0183606