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Fluorescence study of freeze-drying as a method for support the interactions between hyaluronan and hydrophobic species

A freeze-drying method enabling solubilization of hydrophobic species in aqueous solutions of native hyaluronan is described. The method is based on opening the access to supposed hydrophobic patches on hyaluronan by disturbing its massive hydration shell. Hydrophobic and/or polarity-sensitive fluor...

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Detalles Bibliográficos
Autores principales: Michalicová, Petra, Mravec, Filip, Pekař, Miloslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590968/
https://www.ncbi.nlm.nih.gov/pubmed/28886150
http://dx.doi.org/10.1371/journal.pone.0184558