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Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population
The determinants of immunological protection against Mycobacterium tuberculosis (M.tb) infection in humans are not known. Mycobacterial growth inhibition assays have potential utility as in vitro surrogates of in vivo immunological control of M.tb. We evaluated a whole blood growth inhibition assay...
Autores principales: | Baguma, Richard, Penn-Nicholson, Adam, Smit, Erica, Erasmus, Mzwandile, Day, Jonathan, Makhethe, Lebohang, de Kock, Marwou, Hughes, E. Jane, van Rooyen, Michele, Pienaar, Bernadette, Stone, Lynnett, Hanekom, Willem, Brennan, Michael J., Wallis, Robert S., Hatherill, Mark, Scriba, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590973/ https://www.ncbi.nlm.nih.gov/pubmed/28886145 http://dx.doi.org/10.1371/journal.pone.0184563 |
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