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The cardiac calsequestrin gene transcription is modulated at the promoter by NFAT and MEF-2 transcription factors
Calsequestrin-2 (CASQ2) is the main Ca(2+)-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-2 and SRF binding sites within the human CASQ2 gene (hCASQ2) promoter region are functional in neonatal cardiomyocytes. In this work, we investigated i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590987/ https://www.ncbi.nlm.nih.gov/pubmed/28886186 http://dx.doi.org/10.1371/journal.pone.0184724 |