Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

TNF is a pro-inflammatory cytokine produced by both lymphoid and non-lymphoid cells. As a consequence of the widespread expression of its receptors (TNFR1 and 2), TNF plays a role in many important biological processes. In the context of influenza A virus (IAV) infection, TNF has variably been impli...

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Detalles Bibliográficos
Autores principales: Quinn, Kylie M., Kan, Wan-Ting, Watson, Katherine A., Liddicoat, Brian J., Swan, Natasha G., McQuilten, Hayley, Denton, Alice E., Li, Jasmine, Chen, Weisan, Brown, Lorena E., Jackson, David C., Reading, Patrick C., Doherty, Peter C., Kedzierska, Katherine, Kedzierski, Lukasz, Turner, Stephen J., La Gruta, Nicole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590991/
https://www.ncbi.nlm.nih.gov/pubmed/28886201
http://dx.doi.org/10.1371/journal.pone.0184732

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