Cargando…

HLA class I haplotype diversity is consistent with selection for frequent existing haplotypes

The major histocompatibility complex (MHC) contains the most polymorphic genetic system in humans, the human leukocyte antigen (HLA) genes of the adaptive immune system. High allelic diversity in HLA is argued to be maintained by balancing selection, such as negative frequency-dependent selection or...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alter, Idan, Gragert, Loren, Fingerson, Stephanie, Maiers, Martin, Louzoun, Yoram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590998/ https://www.ncbi.nlm.nih.gov/pubmed/28846675 http://dx.doi.org/10.1371/journal.pcbi.1005693

Ejemplares similares

Reply to Hedrick and Klitz: High haplotype discovery rate in the HLA locus
por: Louzoun, Yoram, et al.
Publicado: (2019)

Power Laws for Heavy-Tailed Distributions: Modeling Allele and Haplotype Diversity for the National Marrow Donor Program
por: Slater, Noa, et al.
Publicado: (2015)

Distribution of HLA class I alleles and haplotypes in Korean.
por: Kim, T. G., et al.
Publicado: (1993)

Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans
por: Barquera, Rodrigo, et al.
Publicado: (2020)

Editorial: HLA and KIR Diversity and Polymorphisms: Emerging Concepts
por: Maiers, Martin, et al.
Publicado: (2021)

16(th) IHIW: Global analysis of registry HLA haplotypes from 20 Million individuals: Report from the IHIW Registry Diversity Group
por: Maiers, M, et al.
Publicado: (2013)

HLA-class II haplotypes and Autism Spectrum Disorders
por: Bennabi, Meriem, et al.
Publicado: (2018)

HLA Polymorphisms and Haplotype Diversity in Transylvania, Romania
por: Vică, Mihaela L., et al.
Publicado: (2019)

HLA haplotype frequencies and diversity in patients with hemoglobinopathies
por: Scigliuolo, Graziana M., et al.
Publicado: (2023)

Measuring Ambiguity in HLA Typing Methods
por: Paunić, Vanja, et al.
Publicado: (2012)

PediHaplotyper: software for consistent assignment of marker haplotypes in pedigrees
por: Voorrips, Roeland E., et al.
Publicado: (2016)

Mapping the genetic diversity of HLA haplotypes in the Japanese populations
por: Saw, Woei-Yuh, et al.
Publicado: (2015)

HLA Class I and Class II Conserved Extended Haplotypes and Their Fragments or Blocks in Mexicans: Implications for the Study of Genetic Diversity in Admixed Populations
por: Zúñiga, Joaquín, et al.
Publicado: (2013)

Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition
por: Rao, Xiangyu, et al.
Publicado: (2013)

The Relationship of HLA Class I and II Alleles and Haplotypes with Autism: A Case Control Study
por: Al-Hakbany, Manan, et al.
Publicado: (2014)

HLA Diversity in Saudi Population: High Frequency of Homozygous HLA Alleles and Haplotypes
por: Chentoufi, Aziz Alami, et al.
Publicado: (2022)

HLA Class I and Class II Alleles and Haplotypes Confirm the Berber Origin of the Present Day Tunisian Population
por: Hajjej, Abdelhafidh, et al.
Publicado: (2015)

Insights into HLA-G Genetics Provided by Worldwide Haplotype Diversity
por: Castelli, Erick C., et al.
Publicado: (2014)

Diversity of Extended HLA-DRB1 Haplotypes in the Finnish Population
por: Wennerström, Annika, et al.
Publicado: (2013)

The HLA-DR4 family of haplotypes consists of series of distinct DR and DS molecules
Publicado: (1984)

MHC Haplotyping of SARS-CoV-2 Patients: HLA Subtypes Are Not Associated with the Presence and Severity of COVID-19 in the Israeli Population
por: Ben Shachar, Shay, et al.
Publicado: (2021)

Major Histocompatibility Complex Class I Haplotype Diversity in Chinese Rhesus Macaques
por: Karl, Julie A., et al.
Publicado: (2013)

Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19
por: Pisanti, Simona, et al.
Publicado: (2020)

Influence of HLA Class I Haplotypes on HIV-1 Seroconversion and Disease Progression in Pumwani Sex Worker Cohort
por: Sampathkumar, Raghavan, et al.
Publicado: (2014)

Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis
por: Lammert, Craig, et al.
Publicado: (2019)

HLA Haplotype Mismatch Transplants and Posttransplant Cyclophosphamide
por: Bacigalupo, Andrea, et al.
Publicado: (2016)

HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes
por: Karnaukhov, Vadim, et al.
Publicado: (2022)

High Resolution HLA Analysis Reveals Independent Class I Haplotypes and Amino-Acid Motifs Protective for Multiple Sclerosis
por: Mack, Steven J., et al.
Publicado: (2018)

Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression
por: Jin, Ying, et al.
Publicado: (2019)

Genetic variation within the HLA class III influences T1D susceptibility conferred by high risk HLA haplotypes
por: Valdes, Ana M, et al.
Publicado: (2010)

HLA haplotypes associated with hemochromatosis mutations in the Spanish population
por: Pacho, Arantza, et al.
Publicado: (2004)

HLA-G Haplotypes Are Differentially Associated with Asthmatic Features
por: Ribeyre, Camille, et al.
Publicado: (2018)

Should results of HLA haplotype frequency estimations be normalized?
por: Seitz, Susanne, et al.
Publicado: (2021)

HLA alleles and haplotypes in Sudanese population and their relationship with Mediterraneans
por: Suarez-Trujillo, Fabio, et al.
Publicado: (2023)

SNP-Density Crossover Maps of Polymorphic Transposable Elements and HLA Genes Within MHC Class I Haplotype Blocks and Junction
por: Kulski, Jerzy K., et al.
Publicado: (2021)

SCR-22 of pollen-dominant S haplotype class is recessive to SCR-44 of pollen-recessive S haplotype class in Brassica rapa
por: Wang, Chun-Lei, et al.
Publicado: (2019)

Efficient Sequencing, Assembly, and Annotation of Human KIR Haplotypes
por: Roe, David, et al.
Publicado: (2020)

iHAP – integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
por: Song, Chun Meng, et al.
Publicado: (2006)

Estimating KIR Haplotype Frequencies on a Cohort of 10,000 Individuals: A Comprehensive Study on Population Variations, Typing Resolutions, and Reference Haplotypes
por: Vierra-Green, Cynthia, et al.
Publicado: (2016)

The use of haplotype-specific transcripts improves sample annotation consistency
por: Hartmann, Nicole, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ci905eptefdpglk12b5r2icoqq