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Regulation of podocyte lesions in diabetic nephropathy via miR-34a in the Notch signaling pathway

BACKGROUND: The activation of the Notch signaling pathway has been shown to play an important role in diabetic nephropathy (DN) development. Besides, Notch-1 is a target gene in miR-34a. However, the regulation of the podocyte lesions involved in DN by miR-34a has not been identified. METHODS: This...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangying, Song, Shuping, Luo, Huixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591088/
https://www.ncbi.nlm.nih.gov/pubmed/27858840
http://dx.doi.org/10.1097/MD.0000000000005050