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Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction

In heart failure patients with preserved ejection fraction, their hemodynamic parameters usually change when they are from recumbent to passive leg raising. The authors designed this study to investigate the relationship between hemodynamic parameters measured by impedance cardiography (ICG) and 6-m...

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Autores principales: Zhou, Hong-Lian, Ding, Ling, Mi, Tao, Zheng, Kai, Wu, Xiao-Fen, Wang, Jing, Liu, Meng-Ying, Zhang, Le, Zhang, Cun-Tai, Quan, Xiao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591162/
https://www.ncbi.nlm.nih.gov/pubmed/27858914
http://dx.doi.org/10.1097/MD.0000000000005322
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author Zhou, Hong-Lian
Ding, Ling
Mi, Tao
Zheng, Kai
Wu, Xiao-Fen
Wang, Jing
Liu, Meng-Ying
Zhang, Le
Zhang, Cun-Tai
Quan, Xiao-Qing
author_facet Zhou, Hong-Lian
Ding, Ling
Mi, Tao
Zheng, Kai
Wu, Xiao-Fen
Wang, Jing
Liu, Meng-Ying
Zhang, Le
Zhang, Cun-Tai
Quan, Xiao-Qing
author_sort Zhou, Hong-Lian
collection PubMed
description In heart failure patients with preserved ejection fraction, their hemodynamic parameters usually change when they are from recumbent to passive leg raising. The authors designed this study to investigate the relationship between hemodynamic parameters measured by impedance cardiography (ICG) and 6-minute walk distance (6MWD) of heart failure with preserved ejection fraction (HFPEF). We recruited 49 subjects with HFPEF in the study, and all the subjects were separated into 2 groups: the patients whose hemodynamic parameters rose after passive leg raising were in group 1 (n = 26) and the patients whose hemodynamic parameters did not rise after passive leg raising were in group 2 (n = 23). Our study then compared the 6MWD, left ventricular ejection fraction, and plasma NT-pro-brain natriuretic peptide between the 2 groups. Group 1 had significantly longer 6MWD than group 2 (515.38 ± 24.97 vs 306.39 ± 20.20 m; P = 0.043). Hemodynamic parameters measured by ICG significantly correlated with 6MWD in both groups. Patients whose hemodynamic parameters rose in response to passive leg raising were more likely to have better exercise capacity. Hemodynamic variation in response to passive leg raising measured by ICG may be more sensitive in predicting exercise capacity of patients with HFPEF.
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spelling pubmed-55911622017-09-15 Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction Zhou, Hong-Lian Ding, Ling Mi, Tao Zheng, Kai Wu, Xiao-Fen Wang, Jing Liu, Meng-Ying Zhang, Le Zhang, Cun-Tai Quan, Xiao-Qing Medicine (Baltimore) 3400 In heart failure patients with preserved ejection fraction, their hemodynamic parameters usually change when they are from recumbent to passive leg raising. The authors designed this study to investigate the relationship between hemodynamic parameters measured by impedance cardiography (ICG) and 6-minute walk distance (6MWD) of heart failure with preserved ejection fraction (HFPEF). We recruited 49 subjects with HFPEF in the study, and all the subjects were separated into 2 groups: the patients whose hemodynamic parameters rose after passive leg raising were in group 1 (n = 26) and the patients whose hemodynamic parameters did not rise after passive leg raising were in group 2 (n = 23). Our study then compared the 6MWD, left ventricular ejection fraction, and plasma NT-pro-brain natriuretic peptide between the 2 groups. Group 1 had significantly longer 6MWD than group 2 (515.38 ± 24.97 vs 306.39 ± 20.20 m; P = 0.043). Hemodynamic parameters measured by ICG significantly correlated with 6MWD in both groups. Patients whose hemodynamic parameters rose in response to passive leg raising were more likely to have better exercise capacity. Hemodynamic variation in response to passive leg raising measured by ICG may be more sensitive in predicting exercise capacity of patients with HFPEF. Wolters Kluwer Health 2016-11-04 /pmc/articles/PMC5591162/ /pubmed/27858914 http://dx.doi.org/10.1097/MD.0000000000005322 Text en Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 3400
Zhou, Hong-Lian
Ding, Ling
Mi, Tao
Zheng, Kai
Wu, Xiao-Fen
Wang, Jing
Liu, Meng-Ying
Zhang, Le
Zhang, Cun-Tai
Quan, Xiao-Qing
Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
title Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
title_full Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
title_fullStr Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
title_full_unstemmed Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
title_short Values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
title_sort values of hemodynamic variation in response to passive leg raising in predicting exercise capacity of heart failure with preserved ejection fraction
topic 3400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591162/
https://www.ncbi.nlm.nih.gov/pubmed/27858914
http://dx.doi.org/10.1097/MD.0000000000005322
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