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Transcription factors NRF2 and HSF1 have opposing functions in autophagy
Autophagy plays a critical role in the maintenance of cellular homeostasis by degrading proteins, lipids and organelles. Autophagy is activated in response to stress, but its regulation in the context of other stress response pathways, such as those mediated by heat shock factor 1 (HSF1) and nuclear...
Autores principales: | Dayalan Naidu, Sharadha, Dikovskaya, Dina, Gaurilcikaite, Egle, Knatko, Elena V., Healy, Zachary R., Mohan, Hema, Koh, Glenn, Laurell, Axel, Ball, Graeme, Olagnier, David, de la Vega, Laureano, Ganley, Ian G., Talalay, Paul, Dinkova-Kostova, Albena T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591275/ https://www.ncbi.nlm.nih.gov/pubmed/28887499 http://dx.doi.org/10.1038/s41598-017-11262-5 |
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