Cargando…

Env-Specific Antibodies in Chronic Infection versus in Vaccination

Antibodies are central in vaccine-mediated protection. For HIV-1, a pathogen that displays extreme antigenic variability, B cell responses against conserved determinants of the envelope glycoproteins (Env) are likely required to achieve broadly protective vaccine-induced responses. To understand ant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soldemo, Martina, Karlsson Hedestam, Gunilla B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591324/ https://www.ncbi.nlm.nih.gov/pubmed/28928737 http://dx.doi.org/10.3389/fimmu.2017.01057

Ejemplares similares

HIV-1 Env-Specific Memory and Germinal Center B Cells in C57BL/6 Mice
por: Soldemo, Martina, et al.
Publicado: (2014)

Glutaraldehyde Cross-linking of HIV-1 Env Trimers Skews the Antibody Subclass Response in Mice
por: Soldemo, Martina, et al.
Publicado: (2017)

HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization
por: Navis, Marjon, et al.
Publicado: (2014)

Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque
por: Kaduk, Mateusz, et al.
Publicado: (2022)

Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response
por: Dubrovskaya, Viktoriya, et al.
Publicado: (2017)

VDJ Gene Usage in IgM Repertoires of Rhesus and Cynomolgus Macaques
por: Chernyshev, Mark, et al.
Publicado: (2022)

CD138 and CD31 Double-Positive Cells Comprise the Functional Antibody-Secreting Plasma Cell Compartment in Primate Bone Marrow
por: Martinez-Murillo, Paola, et al.
Publicado: (2016)

Heterozygous Mutation in IκBNS Leads to Reduced Levels of Natural IgM Antibodies and Impaired Responses to T-Independent Type 2 Antigens
por: Pedersen, Gabriel K., et al.
Publicado: (2016)

Flow Cytometry-Based Protocols for the Analysis of Human Plasma Cell Differentiation
por: Khoenkhoen, Sharesta, et al.
Publicado: (2020)

Primary antibody response after influenza virus infection is first dominated by low-mutated HA-stem antibodies followed by higher-mutated HA-head antibodies
por: Aartse, Aafke, et al.
Publicado: (2022)

Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation
por: Martinez, Paola, et al.
Publicado: (2015)

Adaptive immune receptor genotyping using the corecount program
por: Narang, Sanjana, et al.
Publicado: (2023)

Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission
por: Barrows, Brittani M., et al.
Publicado: (2022)

B-1a Cell Development in Splenectomized Neonatal Mice
por: Pedersen, Gabriel K., et al.
Publicado: (2018)

Analysis of IGH allele content in a sample group of rheumatoid arthritis patients demonstrates unrevealed population heterogeneity
por: Hardt, Uta, et al.
Publicado: (2023)

Immunity to SARS‐CoV‐2 induced by infection or vaccination
por: Castro Dopico, Xaquin, et al.
Publicado: (2021)

High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination
por: Dingens, Adam S, et al.
Publicado: (2021)

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses
por: Phad, Ganesh E., et al.
Publicado: (2019)

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
por: Sundling, Christopher, et al.
Publicado: (2010)

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
por: Sundling, Christopher, et al.
Publicado: (2010)

High-Quality Library Preparation for NGS-Based Immunoglobulin Germline Gene Inference and Repertoire Expression Analysis
por: Vázquez Bernat, Néstor, et al.
Publicado: (2019)

Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization
por: Aljedani, Safia S., et al.
Publicado: (2021)

IκBNS expression in B cells is dispensable for IgG responses to T cell-dependent antigens
por: Khoenkhoen, Sharesta, et al.
Publicado: (2022)

Maternal intranasal immunization with HTLV-1 Env induces Env specific antibody responses in breast milk
por: Suzuki, Tadaki
Publicado: (2015)

T(FH) Cells Induced by Vaccination and Following SIV Challenge Support Env-Specific Humoral Immunity in the Rectal-Genital Tract and Circulation of Female Rhesus Macaques
por: Helmold Hait, Sabrina, et al.
Publicado: (2021)

HIV-1 Env Does Not Enable the Development of Protective Broadly Neutralizing Antibodies in an Experimental Autoimmune Encephalomyelitis Mouse Model
por: Siracusano, Gabriel, et al.
Publicado: (2021)

P05-07. Evaluation of peripheral and bone marrow B cell responses in rhesus macaques after immunization with soluble HIV-1 gp140 trimers
por: Sundling, C, et al.
Publicado: (2009)

Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges
por: Lakhashe, Samir K., et al.
Publicado: (2022)

Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage
por: Finkelstein, Maxwell T., et al.
Publicado: (2022)

Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response
por: Bale, Shridhar, et al.
Publicado: (2023)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques
por: Zhao, Fangzhu, et al.
Publicado: (2020)

Profiles of Human Serum Antibody Responses Elicited by Three Leading HIV Vaccines Focusing on the Induction of Env-Specific Antibodies
por: Vaine, Michael, et al.
Publicado: (2010)

OA05-05. Impact of in vivo CD4 binding during HIV-1 Env trimer immunizations of rhesus macaques
por: Douagi, I, et al.
Publicado: (2009)

Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression
por: Wilson, Andrew, et al.
Publicado: (2021)

Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study
por: Perdiguero, Beatriz, et al.
Publicado: (2022)

Repeated Vaccination of Cows with HIV Env gp140 during Subsequent Pregnancies Elicits and Sustains an Enduring Strong Env-Binding and Neutralising Antibody Response
por: Heydarchi, Behnaz, et al.
Publicado: (2016)

Envés
por: Amara, Luigi, 1971-
Publicado: (2003)

Env-Specific IgA from Viremic HIV-Infected Subjects Compromises Antibody-Dependent Cellular Cytotoxicity
por: Ruiz, María Julia, et al.
Publicado: (2015)

Anti-HIV-1 ADCC and HIV-1 Env Can Be Partners in Reducing Latent HIV Reservoir
por: Suryawanshi, Poonam, et al.
Publicado: (2021)

Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies
por: Zhu, Cheng, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n7ilbor4al6gd2m2jh6igsco62