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The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition

Early weaned piglets are vulnerable to diarrhea because of weaning stress and immaturity of intestinal tract. Compelling evidence suggests that gut microbiota is vital to host health. However, it is not well understood on the composition and succession of piglet gut microbiota during the weaning tra...

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Autores principales: Chen, Limei, Xu, Yuesong, Chen, Xiaoyu, Fang, Chao, Zhao, Liping, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591375/
https://www.ncbi.nlm.nih.gov/pubmed/28928724
http://dx.doi.org/10.3389/fmicb.2017.01688
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author Chen, Limei
Xu, Yuesong
Chen, Xiaoyu
Fang, Chao
Zhao, Liping
Chen, Feng
author_facet Chen, Limei
Xu, Yuesong
Chen, Xiaoyu
Fang, Chao
Zhao, Liping
Chen, Feng
author_sort Chen, Limei
collection PubMed
description Early weaned piglets are vulnerable to diarrhea because of weaning stress and immaturity of intestinal tract. Compelling evidence suggests that gut microbiota is vital to host health. However, it is not well understood on the composition and succession of piglet gut microbiota during the weaning transition. In our two trials, total 17 commercial piglets were studied in a pig farm in Jiangxi Province, China. Fresh feces were collected for four times (10 days before weaned, weaned day, 10 days after weaned, 21 days after weaned) by rectal massage. Fecal bacterial composition was assessed by 16S rRNA gene V3–V4 regions sequencing by Illumina Miseq platform. The results showed that the gut microbiota of piglets shifted quickly after weaned and reached relatively stable level in 10 days after weaned. The alpha diversity increased significantly with the age of piglets. The microbiota of suckling piglets was mainly represented by Fusobacterium, Lactobacillus, Bacteroides, Escherichia/Shigella, and Megasphaera. This pattern contrasted with that of Clostridium sensu stricto, Roseburia, Paraprevotella, Clostridium XIVa, and Blautia, which were major representative genera after weaned. In summary, we delineated the development of piglet gut microbiota during the weaning transition. This study helps us understand the maturing development of gut microbiota in commercial piglets.
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spelling pubmed-55913752017-09-19 The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition Chen, Limei Xu, Yuesong Chen, Xiaoyu Fang, Chao Zhao, Liping Chen, Feng Front Microbiol Microbiology Early weaned piglets are vulnerable to diarrhea because of weaning stress and immaturity of intestinal tract. Compelling evidence suggests that gut microbiota is vital to host health. However, it is not well understood on the composition and succession of piglet gut microbiota during the weaning transition. In our two trials, total 17 commercial piglets were studied in a pig farm in Jiangxi Province, China. Fresh feces were collected for four times (10 days before weaned, weaned day, 10 days after weaned, 21 days after weaned) by rectal massage. Fecal bacterial composition was assessed by 16S rRNA gene V3–V4 regions sequencing by Illumina Miseq platform. The results showed that the gut microbiota of piglets shifted quickly after weaned and reached relatively stable level in 10 days after weaned. The alpha diversity increased significantly with the age of piglets. The microbiota of suckling piglets was mainly represented by Fusobacterium, Lactobacillus, Bacteroides, Escherichia/Shigella, and Megasphaera. This pattern contrasted with that of Clostridium sensu stricto, Roseburia, Paraprevotella, Clostridium XIVa, and Blautia, which were major representative genera after weaned. In summary, we delineated the development of piglet gut microbiota during the weaning transition. This study helps us understand the maturing development of gut microbiota in commercial piglets. Frontiers Media S.A. 2017-09-04 /pmc/articles/PMC5591375/ /pubmed/28928724 http://dx.doi.org/10.3389/fmicb.2017.01688 Text en Copyright © 2017 Chen, Xu, Chen, Fang, Zhao and Chen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Chen, Limei
Xu, Yuesong
Chen, Xiaoyu
Fang, Chao
Zhao, Liping
Chen, Feng
The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition
title The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition
title_full The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition
title_fullStr The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition
title_full_unstemmed The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition
title_short The Maturing Development of Gut Microbiota in Commercial Piglets during the Weaning Transition
title_sort maturing development of gut microbiota in commercial piglets during the weaning transition
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591375/
https://www.ncbi.nlm.nih.gov/pubmed/28928724
http://dx.doi.org/10.3389/fmicb.2017.01688
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