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Therapeutic uses of epicatechin in diabetes and cancer

Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments. In this review, we discuss its therapeutic role in the management of two of the most important human disease...

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Autores principales: Abdulkhaleq, Layth Abdulmajeed, Assi, Mohammed Abdulrazzaq, Noor, Mohd Hezmee Mohd, Abdullah, Rasedee, Saad, Mohd Zamri, Taufiq-Yap, Yun Hin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591471/
https://www.ncbi.nlm.nih.gov/pubmed/28919675
http://dx.doi.org/10.14202/vetworld.2017.869-872
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author Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Noor, Mohd Hezmee Mohd
Abdullah, Rasedee
Saad, Mohd Zamri
Taufiq-Yap, Yun Hin
author_facet Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Noor, Mohd Hezmee Mohd
Abdullah, Rasedee
Saad, Mohd Zamri
Taufiq-Yap, Yun Hin
author_sort Abdulkhaleq, Layth Abdulmajeed
collection PubMed
description Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments. In this review, we discuss its therapeutic role in the management of two of the most important human diseases; diabetes and cancer. The consumption of epicatechin has been shown to reduce blood glucose levels in diabetic patients, while is anticancer effect was attributed to its antioxidant properties, antiangiogenic and direct cytotoxicity to cancer cells. Although the exact mechanism of action of epicatechin is still being explored, there is no doubt that it is a promising candidate as an alternative. The significance of this review is to highlight the importance of the usage of natural products (in this case, epicatechin) as an alternative for the treatment of two potentially fatal diseases which is diabetes and cancer. The aim of this review is to educate the scientific community on the role of epicatechin in ameliorating the effects of diabetes and cancers on human while understanding the potential mechanisms of these aforementioned effects.
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spelling pubmed-55914712017-09-15 Therapeutic uses of epicatechin in diabetes and cancer Abdulkhaleq, Layth Abdulmajeed Assi, Mohammed Abdulrazzaq Noor, Mohd Hezmee Mohd Abdullah, Rasedee Saad, Mohd Zamri Taufiq-Yap, Yun Hin Vet World Review Article Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments. In this review, we discuss its therapeutic role in the management of two of the most important human diseases; diabetes and cancer. The consumption of epicatechin has been shown to reduce blood glucose levels in diabetic patients, while is anticancer effect was attributed to its antioxidant properties, antiangiogenic and direct cytotoxicity to cancer cells. Although the exact mechanism of action of epicatechin is still being explored, there is no doubt that it is a promising candidate as an alternative. The significance of this review is to highlight the importance of the usage of natural products (in this case, epicatechin) as an alternative for the treatment of two potentially fatal diseases which is diabetes and cancer. The aim of this review is to educate the scientific community on the role of epicatechin in ameliorating the effects of diabetes and cancers on human while understanding the potential mechanisms of these aforementioned effects. Veterinary World 2017-08 2017-08-06 /pmc/articles/PMC5591471/ /pubmed/28919675 http://dx.doi.org/10.14202/vetworld.2017.869-872 Text en Copyright: © Abdulkhaleq, et al. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review Article
Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Noor, Mohd Hezmee Mohd
Abdullah, Rasedee
Saad, Mohd Zamri
Taufiq-Yap, Yun Hin
Therapeutic uses of epicatechin in diabetes and cancer
title Therapeutic uses of epicatechin in diabetes and cancer
title_full Therapeutic uses of epicatechin in diabetes and cancer
title_fullStr Therapeutic uses of epicatechin in diabetes and cancer
title_full_unstemmed Therapeutic uses of epicatechin in diabetes and cancer
title_short Therapeutic uses of epicatechin in diabetes and cancer
title_sort therapeutic uses of epicatechin in diabetes and cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591471/
https://www.ncbi.nlm.nih.gov/pubmed/28919675
http://dx.doi.org/10.14202/vetworld.2017.869-872
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