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The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury

BACKGROUND: Elderly population (≥ 65) are more prone to develop acute kidney injury (AKI) compared to younger, also elderly with AKI have an increased requirement for dialysis treatment and an elevated risk of short-term and long-term mortality. AIM: The objectives of this study were to examine the...

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Autores principales: Petronijevic, Zvezdana, Selim, Gjulsen, Petkovska, Lidija, Georgievska-Ismail, Ljubica, Spasovski, Goce, Tozija, Liljana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591594/
https://www.ncbi.nlm.nih.gov/pubmed/28932305
http://dx.doi.org/10.3889/oamjms.2017.148
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author Petronijevic, Zvezdana
Selim, Gjulsen
Petkovska, Lidija
Georgievska-Ismail, Ljubica
Spasovski, Goce
Tozija, Liljana
author_facet Petronijevic, Zvezdana
Selim, Gjulsen
Petkovska, Lidija
Georgievska-Ismail, Ljubica
Spasovski, Goce
Tozija, Liljana
author_sort Petronijevic, Zvezdana
collection PubMed
description BACKGROUND: Elderly population (≥ 65) are more prone to develop acute kidney injury (AKI) compared to younger, also elderly with AKI have an increased requirement for dialysis treatment and an elevated risk of short-term and long-term mortality. AIM: The objectives of this study were to examine the effect of treatment of short-term outcomes and mortality in elderly patients with AKI. MATERIAL AND METHODS: Seventy elderly AKI patients, that filled one of the criteria of AKI definition and had hospitalization over 24 hours, were enrolled in the study. RESULTS: The median age of patients was 74.28 ± 6.64, with mean CCI (Charlson Comorbidity Index) score of 6.94 ± 1.94. The majority of patients (70%) were classified at stage 3 of AKIN, 20% of patients were classified at stage 2 and 10% at stage 1. In the groups of patients with death outcome, the chronic cardiomyopathy was more frequently present (p = 0.034). Regarding treatment, 58.6% of the AKI patients underwent hemodialysis while 41.4% received conservative treatment. Mortality rate was 52.8%, out of which 28.6% was in-hospital mortality, while in 24.3% of patients death occurred in the follow-up period of 90 days. CONCLUSION: In our study, short- term survival is not related to different treatment options. Applied treatment in elderly patients with AKI should be assessed by measuring the long term outcome.
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spelling pubmed-55915942017-09-20 The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury Petronijevic, Zvezdana Selim, Gjulsen Petkovska, Lidija Georgievska-Ismail, Ljubica Spasovski, Goce Tozija, Liljana Open Access Maced J Med Sci Clinical Science BACKGROUND: Elderly population (≥ 65) are more prone to develop acute kidney injury (AKI) compared to younger, also elderly with AKI have an increased requirement for dialysis treatment and an elevated risk of short-term and long-term mortality. AIM: The objectives of this study were to examine the effect of treatment of short-term outcomes and mortality in elderly patients with AKI. MATERIAL AND METHODS: Seventy elderly AKI patients, that filled one of the criteria of AKI definition and had hospitalization over 24 hours, were enrolled in the study. RESULTS: The median age of patients was 74.28 ± 6.64, with mean CCI (Charlson Comorbidity Index) score of 6.94 ± 1.94. The majority of patients (70%) were classified at stage 3 of AKIN, 20% of patients were classified at stage 2 and 10% at stage 1. In the groups of patients with death outcome, the chronic cardiomyopathy was more frequently present (p = 0.034). Regarding treatment, 58.6% of the AKI patients underwent hemodialysis while 41.4% received conservative treatment. Mortality rate was 52.8%, out of which 28.6% was in-hospital mortality, while in 24.3% of patients death occurred in the follow-up period of 90 days. CONCLUSION: In our study, short- term survival is not related to different treatment options. Applied treatment in elderly patients with AKI should be assessed by measuring the long term outcome. Republic of Macedonia 2017-08-09 /pmc/articles/PMC5591594/ /pubmed/28932305 http://dx.doi.org/10.3889/oamjms.2017.148 Text en Copyright: © 2017 Zvezdana Petronijevic, Gjulsen Selim, Lidija Petkovska, Ljubica Georgievska-Ismail, Goce Spasovski, Liljana Tozija. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Clinical Science
Petronijevic, Zvezdana
Selim, Gjulsen
Petkovska, Lidija
Georgievska-Ismail, Ljubica
Spasovski, Goce
Tozija, Liljana
The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury
title The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury
title_full The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury
title_fullStr The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury
title_full_unstemmed The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury
title_short The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury
title_sort effect of treatment on short-term outcomes in elderly patients with acute kidney injury
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591594/
https://www.ncbi.nlm.nih.gov/pubmed/28932305
http://dx.doi.org/10.3889/oamjms.2017.148
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