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In Vitro Immunomodulatory Activity of a Transition-State Analog Inhibitor of Human Purine Nucleoside Phosphorylase in Cutaneous Leishmaniasis
Cutaneous leishmaniasis (CL) is the most common clinical form of American tegumentary leishmaniasis caused by Leishmania (Viannia) braziliensis. CL is associated with a strong Th1 immune response. This exacerbated inflammatory response is correlated with severity of disease and delays the healing ti...
Autores principales: | Carvalho, Natália Barbosa, de Oliveira Prates, Fernanda Ventin, da Silva, Rafael de Castro, Dourado, Mayra Elizabeth Ferreira, Amorim, Camila Farias, Machado, Paulo Roberto Lima, Pacheco, Fernanda Grendene, Corte, Temis Weber Furlanetto, Machado, Pablo, Santos, Diógenes Santiago, de Carvalho, Edgar Marcelino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591996/ https://www.ncbi.nlm.nih.gov/pubmed/28929123 http://dx.doi.org/10.1155/2017/3062892 |
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