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Transient Expression of Lumbrokinase (PI239) in Tobacco (Nicotiana tabacum) Using a Geminivirus-Based Single Replicon System Dissolves Fibrin and Blood Clots

Lumbrokinases, a group of fibrinolytic enzymes extracted from earthworm, have been widely used to prevent and treat various cardiovascular diseases. They specifically target fibrin to effectively degrade thrombi without major side effects. Plant expression systems are becoming potential alternative...

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Detalles Bibliográficos
Autores principales:	Dickey, Alexia, Wang, Nan, Cooper, Edwin, Tull, Lauren, Breedlove, Drew, Mason, Hugh, Liu, Dehu, Wang, Kevin Yueju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592424/ https://www.ncbi.nlm.nih.gov/pubmed/28932252 http://dx.doi.org/10.1155/2017/6093017

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