Low hypoxia inducible factor-1α (HIF-1α) expression in testicular germ cell tumors — a major reason for enhanced chemosensitivity?

The molecular basis for enhanced chemosensitivity of testicular germ cell tumors (GCT) has been an area of great interest, as it could potentially give us therapeutic leads in other resistant malignancies. Thus far, however, the increased sensitivity of GCT has been variously attributed to multiple...

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Detalles Bibliográficos
Autores principales: Shenoy, Niraj, Dronca, Roxana, Quevedo, Fernando, Boorjian, Stephen A, Cheville, John, Costello, Brian, Kohli, Manish, Witzig, Thomas, Pagliaro, Lance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592826/
https://www.ncbi.nlm.nih.gov/pubmed/28947870
http://dx.doi.org/10.21147/j.issn.1000-9604.2017.04.11

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