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Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans
The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic b...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592943/ https://www.ncbi.nlm.nih.gov/pubmed/28751501 http://dx.doi.org/10.1534/g3.117.1120 |