Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

Recent genome-wide association studies (GWAS) have identified variants associated with high-density lipoprotein cholesterol (HDL-C) located in or near the ANGPTL8 gene. Given the extensive sharing of GWAS loci across populations, we hypothesized that at least one shared variant at this locus affects...

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Detalles Bibliográficos
Autores principales: Cannon, Maren E., Duan, Qing, Wu, Ying, Zeynalzadeh, Monica, Xu, Zheng, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Civelek, Mete, Lusis, Aldons J., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Tang, Hua, Laakso, Markku, Li, Yun, Mohlke, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592946/
https://www.ncbi.nlm.nih.gov/pubmed/28754724
http://dx.doi.org/10.1534/g3.117.300088

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