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Age-associated changes in granulosa cells and follicular fluid in cows
Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Society for Reproduction and Development
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593084/ https://www.ncbi.nlm.nih.gov/pubmed/28496019 http://dx.doi.org/10.1262/jrd.2017-048 |
| Sumario: | Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa cells and follicular fluid. This review discusses age-associated changes that occur in granulosa cells and follicular fluid in cows and suggests that age-associated decline in granulosa cells and follicular fluid hampers proper oocyte development. |
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