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Age-associated changes in granulosa cells and follicular fluid in cows
Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Society for Reproduction and Development
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593084/ https://www.ncbi.nlm.nih.gov/pubmed/28496019 http://dx.doi.org/10.1262/jrd.2017-048 |
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author | IWATA, Hisataka |
author_facet | IWATA, Hisataka |
author_sort | IWATA, Hisataka |
collection | PubMed |
description | Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa cells and follicular fluid. This review discusses age-associated changes that occur in granulosa cells and follicular fluid in cows and suggests that age-associated decline in granulosa cells and follicular fluid hampers proper oocyte development. |
format | Online Article Text |
id | pubmed-5593084 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Society for Reproduction and Development |
record_format | MEDLINE/PubMed |
spelling | pubmed-55930842017-09-18 Age-associated changes in granulosa cells and follicular fluid in cows IWATA, Hisataka J Reprod Dev SRD Outstanding Research Award 2016 Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa cells and follicular fluid. This review discusses age-associated changes that occur in granulosa cells and follicular fluid in cows and suggests that age-associated decline in granulosa cells and follicular fluid hampers proper oocyte development. The Society for Reproduction and Development 2017-05-12 2017-08 /pmc/articles/PMC5593084/ /pubmed/28496019 http://dx.doi.org/10.1262/jrd.2017-048 Text en ©2017 Society for Reproduction and Development This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | SRD Outstanding Research Award 2016 IWATA, Hisataka Age-associated changes in granulosa cells and follicular fluid in cows |
title | Age-associated changes in granulosa cells and follicular fluid in cows |
title_full | Age-associated changes in granulosa cells and follicular fluid in cows |
title_fullStr | Age-associated changes in granulosa cells and follicular fluid in cows |
title_full_unstemmed | Age-associated changes in granulosa cells and follicular fluid in cows |
title_short | Age-associated changes in granulosa cells and follicular fluid in cows |
title_sort | age-associated changes in granulosa cells and follicular fluid in cows |
topic | SRD Outstanding Research Award 2016 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593084/ https://www.ncbi.nlm.nih.gov/pubmed/28496019 http://dx.doi.org/10.1262/jrd.2017-048 |
work_keys_str_mv | AT iwatahisataka ageassociatedchangesingranulosacellsandfollicularfluidincows |