Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer

Cancers acquire multiple somatic mutations that can lead to the generation of immunogenic mutation-induced neoantigens. These neoantigens can be recognized by the host's immune system. However, continuous stimulation of immune cells against tumor antigens can lead to immune cell exhaustion, whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Czink, Elena, Kloor, Matthias, Goeppert, Benjamin, Fröhling, Stefan, Uhrig, Sebastian, Weber, Tim F., Meinel, Jörn, Sutter, Christian, Weiss, Karl Heinz, Schirmacher, Peter, Doeberitz, Magnus von Knebel, Jäger, Dirk, Springfeld, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593153/
https://www.ncbi.nlm.nih.gov/pubmed/28619747
http://dx.doi.org/10.1101/mcs.a001974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593153/
https://www.ncbi.nlm.nih.gov/pubmed/28619747
http://dx.doi.org/10.1101/mcs.a001974

Ejemplares similares