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A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents

Defects in genes involved in DNA damage repair (DDR) pathway are emerging as novel biomarkers and targets for new prostate cancer drug therapies. A previous report revealed an association between an exceptional response to cisplatin treatment and a somatic loss of heterozygosity (LOH) of FANCA in a...

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Detalles Bibliográficos
Autores principales:	Wilkes, David C., Sailer, Verena, Xue, Hui, Cheng, Hongwei, Collins, Colin C., Gleave, Martin, Wang, Yuzhuo, Demichelis, Francesca, Beltran, Himisha, Rubin, Mark A., Rickman, David S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593159/ https://www.ncbi.nlm.nih.gov/pubmed/28864460 http://dx.doi.org/10.1101/mcs.a001487

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