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The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila
The number of synapses is a major determinant of behavior and many neural diseases exhibit deviations in that number. However, how signaling pathways control this number is still poorly understood. Using the Drosophila larval neuromuscular junction, we show here a PI3K-dependent pathway for synaptog...
Autores principales: | Jordán-Álvarez, Sheila, Santana, Elena, Casas-Tintó, Sergio, Acebes, Ángel, Ferrús, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593197/ https://www.ncbi.nlm.nih.gov/pubmed/28892511 http://dx.doi.org/10.1371/journal.pone.0184238 |
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