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Synthetic high-density lipoprotein nanodisks for targeted withalongolide delivery to adrenocortical carcinoma
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy and has a 5-year survival rate of <35%. ACC cells require cholesterol for steroid hormone production, and this requirement is met via expression on the cell surface of a high level of SRB1, responsible for the uptake of high-density li...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593402/ https://www.ncbi.nlm.nih.gov/pubmed/28919755 http://dx.doi.org/10.2147/IJN.S140591 |