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Breast cancer-associated gene 3 interacts with Rac1 and augments NF-κB signaling in vitro, but has no effect on RANKL-induced bone resorption in vivo

Breast cancer-associated gene 3 (BCA3) is a recently identified adaptor protein whose functions are still being defined. BCA3 has been reported to be an important regulator of nuclear factor-κB (NF-κB) signaling. It has also been reported to interact with the small GTPase, Rac1. Consistent with that...

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Detalles Bibliográficos
Autores principales: Yao, Chen, Yu, Kuan-Ping, Philbrick, William, Sun, Ben-Hua, Simpson, Christine, Zhang, Changqing, Insogna, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593463/
https://www.ncbi.nlm.nih.gov/pubmed/28791343
http://dx.doi.org/10.3892/ijmm.2017.3091

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