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Breast cancer-associated gene 3 interacts with Rac1 and augments NF-κB signaling in vitro, but has no effect on RANKL-induced bone resorption in vivo
Breast cancer-associated gene 3 (BCA3) is a recently identified adaptor protein whose functions are still being defined. BCA3 has been reported to be an important regulator of nuclear factor-κB (NF-κB) signaling. It has also been reported to interact with the small GTPase, Rac1. Consistent with that...
Autores principales: | Yao, Chen, Yu, Kuan-Ping, Philbrick, William, Sun, Ben-Hua, Simpson, Christine, Zhang, Changqing, Insogna, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593463/ https://www.ncbi.nlm.nih.gov/pubmed/28791343 http://dx.doi.org/10.3892/ijmm.2017.3091 |
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