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Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells

BACKGROUND: Whole genome amplification (WGA) is required for single cell genotyping. Effectiveness of currently available WGA technologies in combination with next generation sequencing (NGS) and material preservation is still elusive. RESULTS: In respect to the accuracy of SNP/mutation, indel, and...

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Detalles Bibliográficos
Autores principales: Babayan, Anna, Alawi, Malik, Gormley, Michael, Müller, Volkmar, Wikman, Harriet, McMullin, Ryan P., Smirnov, Denis A., Li, Weimin, Geffken, Maria, Pantel, Klaus, Joosse, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593545/
https://www.ncbi.nlm.nih.gov/pubmed/28915574
http://dx.doi.org/10.18632/oncotarget.10701

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