Cargando…

FoxR2 promotes glioma proliferation by suppression of the p27 pathway

FoxR2 plays an important role in the development of many human tumors. However, the effects of FoxR2 on tumorigenicity of human glioma remain unclear. In this study, we investigated the roles of FoxR2 in cell proliferation and invasion of glioma. We found that overexpression of FoxR2 promoted the pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xuejiao, Liu, Ning, Yue, Chenglong, Wang, Dacheng, Qi, Zhenglei, Tu, Yiming, Zhuang, Guokun, Zhou, Di, Gao, Shangfeng, Niu, Mingshan, Yu, Rutong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593559/ https://www.ncbi.nlm.nih.gov/pubmed/28915588 http://dx.doi.org/10.18632/oncotarget.17447

Ejemplares similares

Smoothened is a poor prognosis factor and a potential therapeutic target in glioma
por: Tu, Yiming, et al.
Publicado: (2017)

CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways
por: Liu, Xuejiao, et al.
Publicado: (2016)

Inhibition of chromosomal region maintenance 1 suppresses the migration and invasion of glioma cells via inactivation of the STAT3/MMP2 signaling pathway
por: Shan, Qianqian, et al.
Publicado: (2020)

High expression of Bruton’s tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma
por: Yue, Chenglong, et al.
Publicado: (2017)

FoxR is an AraC‐like transcriptional regulator of ferrioxamine uptake in Salmonella enterica
por: Saldaña‐Ahuactzi, Zeus, et al.
Publicado: (2022)

PHAP1 promotes glioma cell proliferation by regulating the Akt/p27/stathmin pathway
por: Xie, Manyi, et al.
Publicado: (2018)

miR-202 Suppresses Cell Proliferation by Targeting FOXR2 in Endometrial Adenocarcinoma
por: Deng, Xinchao, et al.
Publicado: (2017)

Reversible inhibitor of CRM1 sensitizes glioblastoma cells to radiation by blocking the NF-κB signaling pathway
por: Liu, Xuejiao, et al.
Publicado: (2020)

The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma
por: Liu, Xuejiao, et al.
Publicado: (2019)

BYSL contributes to tumor growth by cooperating with the mTORC2 complex in gliomas
por: Gao, Shangfeng, et al.
Publicado: (2021)

Effects of Long Form of CAPON Overexpression on Glioma Cell Proliferation are Dependent on AKT/mTOR/P53 Signaling
por: Liang, Dong, et al.
Publicado: (2019)

MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR‐induced NF‐κB activation
por: Liu, Xuejiao, et al.
Publicado: (2020)

Csnk1a1 inhibition modulates the inflammatory secretome and enhances response to radiotherapy in glioma
por: Liu, Guanzheng, et al.
Publicado: (2021)

DIPG-22. DISSECTING THE ONCOGENIC ROLE OF FOXR2 IN DIFFUSE INTRINSIC PONTINE GLIOMA
por: Tsai, Jessica W, et al.
Publicado: (2020)

DIPG-20. DELINEATING MEDIATORS OF ONCOGENESIS IN FOXR2-EXPRESSING DIFFUSE MIDLINE GLIOMAS
por: Tsai, Jessica, et al.
Publicado: (2023)

Management of manifesting FOXRED1 carriers is complex
por: Finsterer, Josef, et al.
Publicado: (2019)

CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells
por: Liu, Xuejiao, et al.
Publicado: (2016)

Low Expression of CAPON in Glioma Contributes to Cell Proliferation via the Akt Signaling Pathway
por: Gao, Shangfeng, et al.
Publicado: (2016)

FOXR2 Promotes the Proliferation, Invasion, and Epithelial–Mesenchymal Transition in Human Colorectal Cancer Cells
por: Lu, Sheng-Qiang, et al.
Publicado: (2017)

Effects of ERK1/2 S-nitrosylation on ERK1/2 phosphorylation and cell survival in glioma cells
por: Jin, Lei, et al.
Publicado: (2018)

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway
por: Gao, Shangfeng, et al.
Publicado: (2017)

ETMR-03. THE ROLE OF FOXR2 IN PEDIATRIC BRAIN CANCER
por: Schmitt-Hoffner, Felix, et al.
Publicado: (2020)

FOXR1 regulates stress response pathways and is necessary for proper brain development
por: Mota, Andressa, et al.
Publicado: (2021)

FoxQ1 Promotes Glioma Cells Proliferation and Migration by Regulating NRXN3 Expression
por: Sun, Hong-Tao, et al.
Publicado: (2013)

Pulmonary hypertension may be secondary in carriers of compound heterozygous FOXRED1 variants
por: Finsterer, Josef
Publicado: (2019)

DIPG-19. FOXR2 is an oncogenic driver across pediatric and adult cancers
por: Tsai, Jessica W, et al.
Publicado: (2022)

RIOK2 is negatively regulated by miR‐4744 and promotes glioma cell migration/invasion through epithelial‐mesenchymal transition
por: Song, Yunnong, et al.
Publicado: (2020)

Chromosome 11q23 aberrations activating FOXR1 in B-cell lymphoma
por: Pommerenke, C, et al.
Publicado: (2016)

FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
por: Tsai, Jessica W., et al.
Publicado: (2022)

FTX Regulated miR-153-3p/FOXR2 to Promote Cisplatin Resistance in Ovarian Cancer
por: Liu, Ming, et al.
Publicado: (2022)

CircABCB10 promotes nonsmall cell lung cancer cell proliferation and migration by regulating the miR‐1252/FOXR2 axis
por: Tian, Xufeng, et al.
Publicado: (2018)

foxr1 is a novel maternal-effect gene in fish that is required for early embryonic success
por: Cheung, Caroline T., et al.
Publicado: (2018)

FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes
por: Liang, Chi-Qian, et al.
Publicado: (2022)

Preclinical evaluation of Mito-LND, a targeting mitochondrial metabolism inhibitor, for glioblastoma treatment
por: Guo, Tongxuan, et al.
Publicado: (2023)

High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency
por: Calvo, Sarah E, et al.
Publicado: (2010)

FOXR2 Stabilizes MYCN Protein and Identifies Non–MYCN-Amplified Neuroblastoma Patients With Unfavorable Outcome
por: Schmitt-Hoffner, Felix, et al.
Publicado: (2021)

Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor
por: Flasch, Diane A., et al.
Publicado: (2022)

The Akt/FoxO/p27(Kip1) axis contributes to the anti‐proliferation of pentoxifylline in hypertrophic scars
por: Yang, Fangfang, et al.
Publicado: (2019)

Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex I deficiency
por: Apatean, Delia, et al.
Publicado: (2019)

Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex 1 deficiency
por: Apatean, Delia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_o18apip2li2ioi191m2tiavcme