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Combination of DESI2 and IP10 gene therapy significantly improves therapeutic efficacy against murine carcinoma

DESI2 (also known as PNAS-4) is a novel pro-apoptotic gene activated during the early response to DNA damage. We previously reported that overexpression of DESI2 induces S phase arrest and apoptosis by activating checkpoint kinases. The present study was designed to test whether combination of DESI2...

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Detalles Bibliográficos
Autores principales: Lin, Chao, Yan, HuaYing, Yang, Jun, Li, Lei, Tang, Mei, Zhao, Xinyu, Nie, Chunlai, Luo, Na, Wei, Yuquan, Yuan, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593561/
https://www.ncbi.nlm.nih.gov/pubmed/28915590
http://dx.doi.org/10.18632/oncotarget.17623