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Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases

The epithelial extracellular membrane-associated serine proteases matriptase, hepsin, and prostasin are proteolytic modifying enzymes of the extracellular domain (ECD) of the epidermal growth factor receptor (EGFR). Matriptase also cleaves the ECD of the vascular endothelial growth factor receptor 2...

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Detalles Bibliográficos
Autores principales:	Chen, Li-Mei, Chai, Karl X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593577/ https://www.ncbi.nlm.nih.gov/pubmed/28915606 http://dx.doi.org/10.18632/oncotarget.17009

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