A genome-wide microRNA profiling indicates miR-424-5p and miR-503-5p as regulators of ALK expression in neuroblastoma

The discovery of missense mutations of ALK gene identified this receptor tyrosine kinase as a therapeutic target in neuroblastoma (NB). Moreover, a high level of ALK protein has been associated with metastatic NB cases and with a worse prognosis, suggesting that also ALK overexpression is involved i...

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Detalles Bibliográficos
Autores principales: De Mariano, Marilena, Stigliani, Sara, Moretti, Stefano, Parodi, Federica, Croce, Michela, Bernardi, Cinzia, Pagano, Aldo, Tonini, Gian Paolo, Ferrini, Silvano, Longo, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593579/
https://www.ncbi.nlm.nih.gov/pubmed/28915608
http://dx.doi.org/10.18632/oncotarget.17033

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