Cargando…
IER3IP1 deficiency leads to increased β-cell death and decreased β-cell proliferation
Mutations in the gene for Immediate Early Response 3 Interacting Protein 1 (IER3IP1) cause permanent neonatal diabetes mellitus in human. The mechanisms involved have not been determined and the role of IER3IP1 in β-cell survival has not been characterized. In order to determine if there is a molecu...
Autores principales: | Sun, Juan, Ren, Decheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593600/ https://www.ncbi.nlm.nih.gov/pubmed/28915629 http://dx.doi.org/10.18632/oncotarget.18179 |
Ejemplares similares
-
IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of β cells
por: Yang, Jing, et al.
Publicado: (2022) -
BH3-Only Molecule Bim Mediates β-Cell Death in IRS2 Deficiency
por: Ren, Decheng, et al.
Publicado: (2014) -
François Ier /
por: Castelot, André
Publicado: (1983) -
IER3 in pancreatic carcinogenesis
por: Molejon, Maria Inés, et al.
Publicado: (2015) -
Role of BH3-Only Molecules Bim and Puma in β-Cell Death in Pdx1 Deficiency
por: Ren, Decheng, et al.
Publicado: (2014)