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Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome

PURPOSE: To investigate how necroptosisis, i.e. programmed necrosis, is involved in MODS, and to examine whether Nec-1, a specific necroptosis inhibitor, ameliorates multiorgan injury in MODS. EXPERIMENTAL DESIGN: A model of MODS was established in six-week old SD rats using fracture trauma followed...

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Detalles Bibliográficos
Autores principales:	Cui, Yao-Li, Qiu, Li-Hua, Zhou, Shi-Yong, Li, Lan-Fang, Qian, Zheng-Zi, Liu, Xian-Ming, Zhang, Hui-Lai, Ren, Xiu-Bao, Wang, Yong-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593618/ https://www.ncbi.nlm.nih.gov/pubmed/28915647 http://dx.doi.org/10.18632/oncotarget.18252

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